Vakona – Developing the acne treatment of tomorrow

Acne vulgaris affects more than 80 percent of people at some point in their life and frequently continues into adulthood. Recent data suggest that there are about 680 million people living with acne around the world. This case focuses on a novel approach to fighting acne without the hazards of antibiotic resistance development.

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Metacurum Biotech AB – Novel antibody treatment for metastatic cancers

MetaCurUm Biotech receieved business support from UBI from 2017 until the autumn of 2025. The company is developing a novel antibody treatment for metastatic cancers. The company´s drug development program is focused on transforming growth factor-beta (TGFβ) driven cancers, with the aim to optimize the treatment paradigms in aggressive forms of cancer with high unmet medical need such as prostate, lung, kidney, and endometrial cancer.

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Xerum – antibody test optimized for self-sampling

During the first two months of the corona pandemic, researchers at the Department of Clinical Microbiology at Umeå University developed a sensitive test of SARS-CoV-2 antibodies, to determine whether a person had covid-19. In May 2020, the antibody test was validated for clinical use in Region Västerbotten, Sweden. This was the start of the company Xerum, which was part of Umeå Biotech Incubator from 2020 to 2023.

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Hiloprobe AB – improved colorectal cancer diagnostics

HiloProbe was a research-based company in the field of cancer diagnostics. HiloProbe developed ColoNode® – a biomarker test for the accurate detection and characterization of cancer cells in the lymph nodes of colorectal cancer patients. At the beginning of 2025, HiloProbe shut down its operations.

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Inficure AB – in vivo validation of fibrotic drug candidates

InfiCure Bio offered advanced drug validation services for pharmaceutical companies developing drugs against fibrosis – or scar tissue formation in organs. The shortage of existing model systems that reflect human fibrotic disease conditions made it an attractive CRO-service for pharmaceutical developers. Due to the pandemic, the company experienced a significant decline in clients, ultimately leading to its closure in the fall of 2023.

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Lipum – a novel treatment of chronic inflammations

Lipum develops a biological pharmaceutical for a novel mechanism of action in the treatment of chronic inflammations. The lead candidate drug (SOL-116) is a monoclonal antibody directed towards the protein bile salt-stimulated lipase, BSSL. One indication is as an orphan drug for the more severe forms of Juvenile Idiopathic Arthritis (JIA), providing patients with an effective treatment alternative having less adverse effects than the drugs used today.

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Nordic Biomarker AB – a manufacturer of latex reagents for coagulation and clinical chemistry analyzers

Nordic Biomarker was founded in 2007 by the biochemist Dr Göran Aronsson and the clinical biochemist Dr Gunnar Pohl. Their business idea didn’t directly come from their research at the time at Umeå University, rather from a clear customer need that they identified after their research period. Today, Nordic Biomarker has the head office in Umeå, a site in Linköping – and customers all over the world.

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HILICON AB

HILICON is a world leading company in developing and manufacturing chromatography products for HILIC (hydrophilic interaction liquid chromatography) separation of polar and hydrophilic compounds. They offer a broad range of HILIC products under the brand names of iHILIC®-Fusion, iHILIC®-Fusion(+), iHILIC®-Fusion(P), and iSPE®-HILIC.  

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MD Biomedical – the startup behind the Onzurf Probe

The company has developed a unique and patented probe and method, Onzurf, which can be used to monitor the status of bodily organs from the surface of the organ in question. The probe provides critical life-saving information for patients, and saves resources for the health care sector.

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Pro Test Diagnostics – the next generation of anti-doping tests

Pro Test Diagnostics has developed a routine test to monitor and detect illegal use of one’s own stored blood to enhance performance in elite athletes. The ABT™-test can expose athletes who have used blood doping and the result is not affected by the athlete’s training intensity, the use of high-altitude training or the use of low oxygen tents.
Update August 2025: Pro Test Diagnostics has secured a significant grant from the World Anti-Doping Agency (WADA).

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Gobroxia AB – neutralizing bacterial exotoxins

A natural compound-approach for neutralizing exotoxins from various gram-negative pathogens. Gobroxia AB has  developed a novel method to treat pathogens causing diseases such as diarrhea, sepsis, tooth loss and whooping cough in humans, as well as bovine respiratory disease in cattle and pneumonia in pigs.

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Betulaceae Pharmaceuticals – improved quality of life during cancer

Our project goals aim at increased survival, improved quality of life and less suffering for cancer patients. Our novel chemical entities (NCE) can prevent over-activation of certain signaling pathways and are based on existing pharmaceuticals that are well tolerable and easy to produce. This will be a first in class drug with little side effects (known drug class), addressing cancer induced cachexia and suppression of the immune system.

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Medsens AB – exact real time prostate cancer diagnosis

By combining two different methods, Medsens AB aimed to offer a whole new tool for realtime microdiagnostics during prostate cancer surgery. Medsens, based on the work of Olof Lindahl och Kerstin Ramser, received support from UBI for three years. The company is put on hold but the research is ongoing.

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Programming cyanobacterial cells for self-aggregation

Cyanobacteria have significant potential as industrial biotechnology platforms to produce a wide variety of bio-products, such as polymers, sugars and powerful antioxidants such as C-phycocyanin. Our team have created a set of genetic tools that give significant advantages in the microalgae industry for save, efficient and specific bioproduction.

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