Tanomed AB – developed a unique nasal spray

Tanomed has developed a unique nasal spray to relieve and prevent the progression of the common cold by reinforcing the body’s own defenses. The patented technology is based on Swedish research carried out in cooperation with Umeå University and with business development support from the Umeå Biotech Incubator. The company was sold to Karo Bio AB in spring 2015.

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Mucocort – treating recurrent aphthous ulcers

We are developing an oral patch, with a pending patented galenic formulation, providing immediate pain relief. The product can theoretically reach a target patient population of 10-20,000 patients annually in Sweden, and considerably higher in international markets.

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Gobroxia AB – neutralizing bacterial exotoxins

A natural compound-approach for neutralizing exotoxins from various gram-negative pathogens. Gobroxia AB has  developed a novel method to treat pathogens causing diseases such as diarrhea, sepsis, tooth loss and whooping cough in humans, as well as bovine respiratory disease in cattle and pneumonia in pigs.

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Quretech Bio – fighting bacterial virulence

Quretech Bio develops innovative antibiotics by stopping bacterial virulence with a first-in-class active substance. The approach is not to kill bacteria, but make them harmless – thus complementing existing treatments and making established antibiotic drugs more effective without causing resistance.

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Metacurum Biotech AB – Novel antibody treatment for metastatic cancers

MetaCurUm Biotech is developing a novel antibody treatment for metastatic cancers. The company´s drug development program is focused on transforming growth factor-beta (TGFβ) driven cancers, with the aim to optimize the treatment paradigms in aggressive forms of cancer with high unmet medical need such as prostate, lung, kidney, and endometrial cancer.

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A novel treatment of acne vulgaris based on anti-biofilm protein

Acne vulgaris affects more than 80 percent of people at some point in their life and frequently continues into adulthood. Recent data suggest that there are about 700 million people living with acne around the world. This case focuses on a novel approach to fighting acne without the hazards of antibiotic resistance development.

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Morphobloc – new antifungal agents blocking virulence

Current drugs against mycoses are toxic. We aim to develop a new class of antifungal agents that disarm the invasive forms of fungal cells instead of merely eradicating them. This has two advantages: The new compounds are less aggressive for the host and resistance development is reduced.

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Lipum – a novel treatment of chronic inflammations

Lipum develops a biological pharmaceutical for a novel mechanism of action in the treatment of chronic inflammations. The lead candidate drug (SOL-116) is a monoclonal antibody directed towards the protein bile salt-stimulated lipase, BSSL. One indication is as an orphan drug for the more severe forms of Juvenile Idiopathic Arthritis (JIA), providing patients with an effective treatment alternative having less adverse effects than the drugs used today.

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Betula Pharma – improved quality of life during cancer

Our project goals aim at increased survival, improved quality of life and less suffering for cancer patients. Our novel chemical entities (NCE) can prevent over-activation of certain signaling pathways and are based on existing pharmaceuticals that are well tolerable and easy to produce. This will be a first in class drug with little side effects (known drug class), addressing cancer induced cachexia and suppression of the immune system.

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