Inficure AB – in vivo validation of fibrotic drug candidates

InfiCure Bio offer advanced drug validation services for pharmaceutical companies developing drugs against fibrosis – or scar tissue formation in organs. The shortage of existing model systems that reflect human fibrotic disease conditions, make this a very attractive CRO-service for pharmaceutical developers.

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Lipum – a novel treatment of chronic inflammations

Lipum develops a biological pharmaceutical for a novel mechanism of action in the treatment of chronic inflammations. The lead candidate drug (SOL-116) is a monoclonal antibody directed towards the protein bile salt-stimulated lipase, BSSL. One indication is as an orphan drug for the more severe forms of Juvenile Idiopathic Arthritis (JIA), providing patients with an effective treatment alternative having less adverse effects than the drugs used today.

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Medsens AB – exact real time prostate cancer diagnosis

By combining two different methods, Medsens AB is aiming at offering a whole new tool for realtime microdiagnostics during prostate cancer surgery. The company’s instrument is far more accurate that the methods used by clinicians today – which could make surginal procedures much more efficient. The project is based on the work of Olof Lindahl och Kerstin Ramser.

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Metacurum Biotech AB – Novel antibody treatment for metastatic cancers

MetaCurUm Biotech is developing a novel antibody treatment for metastatic cancers. The company´s drug development program is focused on transforming growth factor-beta (TGFβ) driven cancers, with the aim to optimize the treatment paradigms in aggressive forms of cancer with high unmet medical need such as prostate, lung, kidney, and endometrial cancer.

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Programming cyanobacterial cells for self-aggregation

Cyanobacteria have significant potential as industrial biotechnology platforms to produce a wide variety of bio-products, such as polymers, sugars and powerful antioxidants such as C-phycocyanin. Our team have created a set of genetic tools that give significant advantages in the microalgae industry for save, efficient and specific bioproduction.

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Mucocort – Oral patch for instant pain relief and faster healing of Recurrent Apthous Ulcers (RAS)

Recurrent aphthous ulcers (RAS) are mouth ulcers that can last for more than a week at each occasion and during that period patients often suffer and need sick leave. About 80% of all patient’s state that the pain from RAS is the main symptom. The innovative oral patch (MO45A) shields the ulcer giving instant pain relief and improves healing primarily through it´s extensive hygroscopic effect.

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Morphobloc – new antifungal agents blocking virulence

Current drugs against mycoses are toxic. We aim to develop a new class of antifungal agents that disarm the invasive forms of fungal cells instead of merely eradicating them. This has two advantages: The new compounds are less aggressive for the host and resistance development is reduced.

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Pro Test Diagnostics – the next generation of anti-doping tests

Pro Test Diagnostics has developed a routine test to monitor and detect illegal use of one’s own stored blood to enhance performance in elite athletes. The ABT™-test can expose athletes who have used blood doping and the result is not affected by the athlete’s training intensity, the use of high-altitude training or the use of low oxygen tents.

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Gobroxia AB – neutralizing bacterial exotoxins

A natural compound-approach for neutralizing exotoxins from various gram-negative pathogens. Gobroxia AB has  developed a novel method to treat pathogens causing diseases such as diarrhea, sepsis, tooth loss and whooping cough in humans, as well as bovine respiratory disease in cattle and pneumonia in pigs.

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