UmanDiagnostics

Neurofilaments are the main cytoskeletal constituents in neuronal cells. They are important for the velocity of nerve impulses. Following injuries of nerve cells due to direct trauma or slow degenerative processes, the content of the cell is released into the surrounding compartment allowing quantitative determinations of the axonal proteins. Increased levels of neurofilament light have been found in different degenerative diseases such as Amyotrophic lateral sclerosis, Alzheimers disease, Multiple sclerosis and in animals with chronic experimental autoimmune encephalomyelitis. The new UmanDiagnostics NF-light® ELISA is designed for quantitative determinations of NF-L in human body fluids. The assay will be valuable both for diagnostic and therapeutic purposes.

Niklas Norgren, Torgny Stigbrand
UmanDiagnostics AB, Tvistevägen
48, Box 7995, SE-907 36 Umeå,
Sweden

www.umandiagnostics.com