Creative Antibiotics AB
Creative Antibiotics was founded in 2000, under the name
Innate Pharmaceuticals, to commercialize world leading
research at Umeå University and Karolinska Institutet. The company
identifies compounds and develops candidate drugs up to and
including limited clinical trials in patients. Creative Antibiotics
develops Virulence Blocking Agents, a novel class of antibacterial
drugs that may complement or replace antibiotics.
Virulence blockers disarm rather that destroy pathogenic
bacteria but leave beneficial bacteria intact, which reduces the
risk of the bacteria developing resistance to medicines. They may
offer an advantage over conventional antibiotics as drug resistance
is predicted to be less likely to develop.
Three medicines are being developed; Medicines against
Diarrhoeal disease, Sexually transmitted infections and Nosocomial
infections in severe burns.
Creative Antibiotics collaborates with an Indian company,
Syngene International Ltd, in the Diarrhoea Project. In the second
project, Innate is collaborating with Umeå University and
University of Callifornia, Irvine, USA. The European Medicines
Agency (EMEA) has designated Creative Antibiotics' compound INP 341
as an orphan medicinal product for the treatment of severe burns.
This designation can dramatically reduce the development costs and
reach the market sooner.
Creative Antibiotics has also a collaboration agreement with
Griffith University, Brisbane, Australia. The University has built
up a world-leading collection of natural produts that gives
Creative Antibiotics the opportunity to develop novel antibacterial
medicines that may represent the future of anti-bacterial therapy.
A collection of 200.000 natural product fractions will be screened
using Creative Antibiotics' platform technology to find virulence
blockers.
http://www.creativeantibiotics.com/